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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D9B
All Species:
11.52
Human Site:
S435
Identified Species:
28.15
UniProt:
Q66K14
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q66K14
NP_055858.2
1250
140498
S435
E
Q
P
A
S
P
A
S
P
L
S
S
R
Q
S
Chimpanzee
Pan troglodytes
XP_001139147
1448
162825
A625
Q
R
S
T
S
S
D
A
D
G
E
R
Q
F
N
Rhesus Macaque
Macaca mulatta
XP_001090502
1222
138535
A399
Q
R
S
T
S
S
D
A
D
G
E
R
Q
F
N
Dog
Lupus familis
XP_538581
1558
172372
T737
D
Q
L
A
S
P
T
T
P
L
G
S
R
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5SVR0
1263
141761
S436
E
P
P
A
S
P
S
S
P
L
S
S
P
P
S
Rat
Rattus norvegicus
NP_001101744
1262
141849
S436
E
P
P
T
S
P
T
S
P
L
S
S
P
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506944
844
94353
L102
L
K
G
I
P
E
T
L
R
G
E
L
W
L
L
Chicken
Gallus gallus
XP_414602
1261
143708
T439
S
P
L
A
V
S
P
T
S
A
L
N
N
R
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0W9
1108
126719
L367
C
L
R
G
K
R
A
L
R
F
S
E
V
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53258
950
109241
V209
Y
P
G
N
P
T
M
V
K
E
K
A
K
L
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.3
61.4
74.5
N.A.
91.7
91.5
N.A.
53.6
79.2
N.A.
46.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
66.5
74
76.1
N.A.
94.6
94
N.A.
59.2
87.2
N.A.
63.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
66.6
N.A.
73.3
66.6
N.A.
0
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
40
80
N.A.
80
66.6
N.A.
6.6
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
40
0
0
20
20
0
10
0
10
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
20
0
20
0
0
0
0
0
10
% D
% Glu:
30
0
0
0
0
10
0
0
0
10
30
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
20
0
% F
% Gly:
0
0
20
10
0
0
0
0
0
30
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
10
0
0
0
10
0
10
0
10
0
0
% K
% Leu:
10
10
20
0
0
0
0
20
0
40
10
10
0
30
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
10
10
0
20
% N
% Pro:
0
40
30
0
20
40
10
0
40
0
0
0
20
10
10
% P
% Gln:
20
20
0
0
0
0
0
0
0
0
0
0
20
20
0
% Q
% Arg:
0
20
10
0
0
10
0
0
20
0
0
20
20
20
10
% R
% Ser:
10
0
20
0
60
30
10
30
10
0
40
40
0
0
40
% S
% Thr:
0
0
0
30
0
10
30
20
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _